NAD+ supports sirtuins
Between 1990 and 2022, obesity prevalence among Hispanic males more than doubledfrom 17.4% to 42.6%with Hispanic females showing nearly identical increases
However, interpretation remains cautious, as reproductive endpoints (ongoing pregnancy, live birth) are inconsistently reported and dosing (commonly 24 g/day), formulations (MI alone vs 40:1 MI: DCI), co-therapies, and trial quality vary widely, prompting calls for larger, standardized, phenotype-stratified studies
KN has received honoraria from AstraZeneca, Bayer, Boehringer Ingelheim Japan, Daiichi Sankyo, Eli Lilly Japan, Kowa, Mitsubishi Tanabe, MSD, Novartis, Novo Nordisk, and Otsuka
Vanderbilt University Medical Center is studying whether the drugs could help adults with obesity and asthma, with researchers expecting results during the first half of 2027